What are Nanoparticles and How Do They Enhance Affinity Chromatography?
Nanoparticles are particles with dimensions in the nanometer scale, typically ranging from 1 to 100 nanometers. These particles exhibit unique physical and chemical properties due to their small size and large surface area. In affinity chromatography, nanoparticles can be functionalized with specific ligands to increase the binding efficiency and selectivity for the target molecules. This results in higher purification yields and enhanced sensitivity.