Fusogenic lipids are generally composed of a hydrophilic head and one or more hydrophobic tails, similar to other lipids. However, their unique structural characteristics enable them to destabilize and merge with cell membranes. Common examples include dioleoylphosphatidylethanolamine (DOPE) and cholesteryl hemisuccinate (CHEMS), which are often utilized in liposomal formulations to enhance membrane fusion.
