Enhanced Permeability: The chimeric nature of these CPPs improves their ability to cross cellular membranes compared to traditional CPPs. Stimuli-Responsiveness: Their "smart" functionality allows for controlled release in response to environmental triggers, improving targeting accuracy. Biocompatibility: As peptides, they are generally more biocompatible than synthetic carriers, minimizing immune response and toxicity. Versatility: They can be tailored for a range of applications, from gene therapy to protein delivery.