Several strategies can be employed to mitigate beam damage:
Low Dose Imaging: Reducing the beam current and exposure time can minimize damage while still obtaining necessary information. Cooling: Cooling the sample with liquid nitrogen or helium can reduce thermal effects and radiolysis. Coating: Applying conductive or protective coatings can help in reducing charging and physical damage. Advanced Imaging Techniques: Techniques such as cryo-electron microscopy (Cryo-EM) can be utilized to study samples in their native state with minimal damage.
