How is the Bone Marrow Micronucleus Test Conducted?
This test involves administering the nanomaterial to a test subject, typically a rodent, and subsequently examining the bone marrow cells for the presence of micronuclei. The procedure includes:
1. Exposure: The test subject is exposed to the nanomaterial via inhalation, ingestion, or injection. 2. Sample Collection: Bone marrow cells are collected from the femur or another suitable bone. 3. Staining and Analysis: The cells are stained using specific dyes, and the presence of micronuclei is observed under a microscope.
