How Does Solid State NMR Differ from Solution NMR?
The primary difference between solid state NMR and solution NMR lies in the state of the sample. In solution NMR, molecules are free to tumble, averaging out magnetic interactions. However, in solid state NMR, the molecules are fixed, resulting in broad spectral lines. Techniques such as magic-angle spinning (MAS) and cross-polarization (CP) are employed to enhance spectral resolution and sensitivity.
