The process of SFS typically involves dissolving precursors in a supercritical fluid, followed by rapid expansion or decompression to precipitate nanoparticles. There are various methods within SFS, including:
Rapid Expansion of Supercritical Solutions (RESS): This involves dissolving solute in supercritical fluid and rapidly expanding through a nozzle to form nanoparticles. Supercritical Anti-Solvent (SAS): Here, a solution of the precursor is mixed with supercritical fluid, causing the solute to precipitate as nanoparticles due to a decrease in solubility. Gas Anti-Solvent Recrystallization (GAS): Similar to SAS, but the supercritical fluid is added to a liquid solution of the precursor, leading to nanoparticle formation.
