Nanotechnology enhances solubility through several mechanisms:
1. Particle Size Reduction: By reducing the size of particles to the nanoscale, the surface area-to-volume ratio increases, which enhances the dissolution rate. 2. Surface Modification: Functionalizing the surface of nanoparticles with hydrophilic groups can improve their interaction with water, thereby increasing solubility. 3. Nanocarriers: Encapsulating poorly soluble drugs in nanocarriers like liposomes, dendrimers, or micelles can improve their solubility and stability.