Nanotechnology offers innovative ways to enhance ICD by improving the delivery and efficacy of therapeutic agents. Nanoparticles can be engineered to deliver chemotherapeutic drugs, photosensitizers, or immune adjuvants directly to the tumor site, thereby increasing the local concentration of these agents and minimizing systemic side effects. Additionally, nanoparticles can be designed to release their payload in response to specific tumor microenvironment conditions, ensuring a targeted and controlled release.