Metal ion release can occur through several pathways:
Dissolution: Nanoparticles dissolve in aqueous environments, releasing metal ions. Oxidation: Metal nanoparticles oxidize, leading to the formation of metal ions. Interaction with Biological Systems: Interaction with proteins, cells, or other biological molecules can trigger the release of metal ions.
Factors such as pH, temperature, and the presence of other chemicals can influence the rate and extent of metal ion release.