Abraxane utilizes nanoparticles to deliver the active drug paclitaxel. These nanoparticles are composed of paclitaxel bound to albumin, a naturally occurring protein in the human body. This formulation allows for a more efficient delivery system, as the albumin helps the drug to circumvent some of the body's natural defenses against foreign substances. Once in the bloodstream, the nanoparticles are absorbed by the tumor cells more effectively than traditional formulations of paclitaxel.