Nanoparticles can be engineered to carry neuroprotective drugs and release them in a controlled manner. They can be designed to cross the blood-brain barrier and specifically target damaged or degenerating neurons. This targeted delivery system ensures that a higher concentration of the drug reaches the affected areas, thereby maximizing efficacy and reducing systemic toxicity. Additionally, nanoparticles can be functionalized with ligands that bind to specific receptors on neurons, further enhancing their targeting capabilities.