Nanocarriers achieve targeted delivery through several mechanisms:
1. Passive targeting: Exploiting the enhanced permeability and retention (EPR) effect in tumor tissues. 2. Active targeting: Functionalizing nanocarriers with ligands or antibodies that bind specifically to receptors on target cells. 3. Stimuli-responsive delivery: Designing nanocarriers that release their payload in response to specific stimuli such as pH, temperature, or enzymes.