How Do Gadolinium Based Nanoparticles Work in MRI?
In MRI, gadolinium-based contrast agents work by altering the relaxation times of protons in water molecules within the body, thus enhancing the contrast of the images. When gadolinium is encapsulated in nanoparticles, it can be delivered more effectively to specific areas in the body. This targeting capability is achieved by modifying the surface of the nanoparticles with specific ligands that bind to certain types of cells or tissues, such as cancer cells.
