Compliance involves several steps. First, companies must identify and characterize the chemicals they use in nanotechnology. This includes understanding the chemical composition, particle size, shape, and surface properties. Next, they must conduct risk assessments to evaluate the potential hazards. This often involves in vitro and in vivo testing, as well as computational modeling. Finally, companies must implement safety measures, such as using less hazardous alternatives, engineering controls to limit exposure, and personal protective equipment (PPE) for workers.