1. Risk Assessment: Conduct thorough risk assessments to identify potential hazards and evaluate the likelihood and severity of adverse effects. This includes studying the material's physicochemical properties, biological interactions, and exposure scenarios. 2. Engineering Controls: Implement engineering controls such as containment, ventilation, and filtration systems to minimize exposure to nanomaterials during manufacturing and handling. 3. Personal Protective Equipment (PPE): Use appropriate PPE, including gloves, masks, and protective clothing, to safeguard workers from direct exposure to nanomaterials. 4. Labeling and Documentation: Ensure accurate labeling and comprehensive documentation of nanomaterials, including safety data sheets (SDS), to inform users about potential risks and safe handling practices.