Traditional diagnostic methods like sputum smear microscopy and culture tests are time-consuming and often lack sensitivity. Nanotechnology offers advanced diagnostic tools with higher sensitivity and specificity. Nanoparticles, such as gold nanoparticles, can be functionalized to detect TB bacteria or its genetic material with greater accuracy. Quantum dots and nanosensors are other promising tools that can allow for rapid, point-of-care testing, potentially reducing the diagnostic time from weeks to hours.