How Are Nanoparticles Functionalized with Monoclonal Antibodies?
Functionalization involves attaching mAbs to the surface of nanoparticles. This is typically achieved through chemical conjugation methods such as covalent bonding or biotin-streptavidin linkage. Proper functionalization ensures that the mAbs retain their antigen-binding ability and enhances the targeting specificity of the nanoparticles.