Cavitation nuclei can be generated through several methods: 1. Physical Methods: Techniques like ultrasonic irradiation and hydrodynamic flow can create cavitation nuclei by introducing microbubbles or particles into a liquid. 2. Chemical Methods: Chemical reactions can produce gas bubbles or solid particles that act as cavitation nuclei. 3. Biological Methods: Certain biological processes, such as the activity of microorganisms, can also generate cavitation nuclei.