How Are Animal Models Selected for Nanotechnology Research?
The selection of an appropriate animal model depends on several factors, including:
Research Objectives: The specific goals of the study, such as toxicity assessment, therapeutic efficacy, or biodistribution. Biological Relevance: The closeness of the animal's physiological and genetic characteristics to humans. Regulatory Requirements: Guidelines set by regulatory bodies for preclinical testing. Ethical Considerations: The ethical implications of using certain animals, especially higher mammals like primates.