Are There Any Challenges Associated with This Method?
Yes, there are challenges such as:
1. Size and Surface Characteristics: The size, shape, and surface charge of nanoparticles can significantly affect their ability to utilize clathrin mediated endocytosis. 2. Biological Barriers: Nanoparticles must navigate various biological barriers such as the extracellular matrix and the cell membrane. 3. Possible Immune Responses: The immune system may recognize and eliminate nanoparticles before they reach their target cells.
