Rik Gijsbers - Nanotechnology

Author Information

Rik Gijsbers is affiliated with the Department of Pharmaceutical and Pharmacological Sciences, Laboratory for Viral Vector Technology and Gene Therapy at KU Leuven in Belgium. His work primarily focuses on the development and application of viral vectors for gene therapy, as well as the study of their genotoxicity and safety profiles.

Research Contributions

Rik Gijsbers has made significant contributions to the field of nanotechnology and gene therapy. His recent work includes studies on luminescent human iPSC-derived neurospheroids for neurotoxicity modeling, urine-derived kidney progenitor cells in cystinosis, and CRISPR/Cas9-induced mutagenesis for HIV-1 nuclear import. Additionally, his research encompasses the development of improved viral vectors and genome editing technologies, as well as the transcriptional profiling of STAT1 gain-of-function mutations.

Aliases

The author is also known by the aliases R Gijsbers and R. Gijsbers.

Publication and Citation Metrics

Metric	Value
Total Citation Count	6158
H-index	46
Total Paper Count	311

Publications:

Luminescent Human iPSC-Derived Neurospheroids Enable Modeling of Neurotoxicity After Oxygen-glucose Deprivation.

DOI: 10.1007/s13311-022-01212-z

Year: 2022

Urine-Derived Kidney Progenitor Cells in Cystinosis

DOI: 10.3390/cells11071245

Year: 2022

BET-independent MLV integration is retargeted in vivo and selects distinct genomic elements for lymphomagenesis

DOI: 10.1101/2022.02.23.481640

Year: 2022

CRISPR/Cas9-Induced Mutagenesis Corroborates the Role of Transportin-SR2 in HIV-1 Nuclear Import

DOI: 10.1128/Spectrum.01336-21

Year: 2021

Baboon Envelope Pseudotyped “Nanoblades” Carrying Cas9/gRNA Complexes Allow Efficient Genome Editing in Human T, B, and CD34+ Cells and Knock-in of AAV6-Encoded Donor DNA in CD34+ Cells

DOI: 10.3389/fgeed.2021.604371

Year: 2021

Transcriptional Profiling of STAT1 Gain-of-Function Reveals Common and Mutation-Specific Fingerprints

DOI: 10.3389/fimmu.2021.632997

Year: 2021

Improved functionality and potency of next generation BinMLV viral vectors toward safer gene therapy

DOI: 10.1016/j.omtm.2021.07.003

Year: 2021

Cardiac Microvascular Endothelial Cells in Pressure Overload-Induced Heart Disease.

DOI: 10.1161/CIRCHEARTFAILURE.120.006979

Year: 2021

Predicting genotoxicity of viral vectors for stem cell gene therapy using gene expression-based machine learning.

DOI: 10.1016/j.ymthe.2021.06.017

Year: 2021

Live Cell Imaging Demonstrates Multiple Routes Toward a STAT1 Gain-of-Function Phenotype

DOI: 10.3389/fimmu.2020.01114

Year: 2020

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