Jürgen Götz - Nanotechnology

Author Information

Jürgen Götz is a prominent researcher affiliated with the Clem Jones Centre for Ageing Dementia Research at the Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia. His research primarily focuses on the mechanisms underlying Alzheimer's disease and other neurodegenerative conditions. His work involves innovative techniques for studying the blood-brain barrier, tau proteins, and microglial and astrocyte cultures.

Research Contributions

Jürgen Götz has made significant contributions to the field of neuroscience, particularly in Alzheimer’s disease research. In 2022 alone, he published several groundbreaking papers. These include studies on the blood-brain barrier model for developing ultrasound-mediated delivery of Aducanumab and anti-Tau antibodies, the dynamics of tau proteins, and the isolation and culture of pure adult mouse microglia and astrocytes. Additionally, his work has explored focused ultrasound-mediated opening in the blood-brain barrier and the mechanisms by which exosomal tau seeds escape into the cytosol. His research is instrumental in understanding and developing therapeutic strategies for neurodegenerative diseases.

Aliases

Jürgen Götz is also known by several aliases including Jürgen Götz, Jürgen Götz, J. Götz, and Jürg Götz.

Publication and Citation Metrics

Metric	Value
Number of Papers	284
Number of Citations	20,753
h-index	74

Publications:

A sporadic Alzheimer’s blood-brain barrier model for developing ultrasound-mediated delivery of Aducanumab and anti-Tau antibodies

DOI: 10.1101/2022.03.06.483200

Year: 2022

Tau forms dynamic hot spots that are resistant to microtubule perturbations and cholesterol depletion

DOI:

Year: 2022

Isolation and culture of pure adult mouse microglia and astrocytes for in vitro characterization and analyses

DOI: 10.1016/j.xpro.2022.101295

Year: 2022

Single-molecule imaging reveals Tau trapping at nanometer-sized dynamic hot spots near the plasma membrane

DOI: 10.1101/2022.02.04.479198

Year: 2022

Claudin-5 binder enhances focused ultrasound-mediated opening in an in vitro blood-brain barrier model

DOI: 10.7150/thno.65539

Year: 2022

De novo proteomic methods for examining the molecular mechanisms underpinning long-term memory

DOI: 10.1016/j.brainresbull.2020.12.015

Year: 2021

Altered ribosomal function and protein synthesis caused by tau

DOI: 10.1186/s40478-021-01208-4

Year: 2021

Claudin-5 binder enhances focused ultrasound-mediated opening in an in vitro blood-brain barrier model

DOI: 10.1101/2021.08.01.454692

Year: 2021

Alzheimer's disease research progress in Australia: The Alzheimer's Association International Conference Satellite Symposium in Sydney

DOI: 10.1002/alz.12380

Year: 2021

Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol

DOI: 10.1007/s00401-020-02254-3

Year: 2021

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