Resolution: Achieving high enough resolution to see individual atoms or molecules.
Sample Preparation: Preparing samples that are thin enough for electron microscopy without altering their properties.
Environment: Maintaining an appropriate environment, such as a vacuum, to prevent contamination and damage.
High-Resolution TEM: Newer TEMs can achieve
sub-angstrom resolution, allowing for the visualization of atomic structures.
In-situ Microscopy: Techniques that allow for the observation of dynamic processes in real-time, such as
chemical reactions.
Super-Resolution Microscopy: Methods like STED and PALM that overcome the diffraction limit of light, providing nanometer-scale resolution.
Drug Delivery: Understanding how nanoparticles interact with cells helps in designing efficient
drug delivery systems.
Electronics: Observing electron behaviors in nanoscale semiconductors aids in the development of faster and more efficient
electronic devices.
Energy: Studying nanomaterials used in
solar cells and batteries leads to more efficient energy storage and conversion.
Integration of AI: Using
artificial intelligence to analyze complex data sets from nanoscale observations.
Hybrid Techniques: Combining different microscopy methods to provide a more comprehensive understanding of nanomaterials.
Improved Resolution: Continuing to push the limits of resolution to observe even smaller structures with greater detail.