Despite its potential, protein design faces several challenges:
- Predictive Accuracy: Current computational models are not always accurate in predicting how a designed protein will fold and function. - Complexity: The vast number of possible amino acid sequences makes it difficult to explore all potential designs. - Stability: Designed proteins must be stable under physiological conditions, which is not always easy to achieve. - Scalability: Producing designed proteins in large quantities can be challenging and costly.
