Leonid A. Mirny - Nanotechnology

Author Information

Leonid A. Mirny is a distinguished researcher affiliated with the Institute for Medical Engineering and Science, and the Department of Physics at the Massachusetts Institute of Technology (MIT), located at 77 Massachusetts Ave., Cambridge, MA 02139, USA.

Research Contributions

Leonid A. Mirny's research predominantly focuses on the spatial organization of chromatin and its implications on gene expression and cellular function. In 2022 alone, he has co-authored several significant papers such as "Spatial organization of transcribed eukaryotic genes," "Chromatin micromanipulation in live cells," and "Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging." His work often involves cutting-edge techniques like live-cell imaging and chromatin micromanipulation to unravel the complexities of chromatin organization and its dynamic nature. His contributions have significantly advanced our understanding of genomic architecture and its regulatory mechanisms.

Aliases

Leonid A. Mirny is also known by various aliases including Leonid Mirny, L Mirny, L. A. Mirny, L A Mirny, and L. Mirny.

Publication and Citation Metrics

Publication Count	Citation Count	h-index
221	32324	77

Publications:

Spatial organization of transcribed eukaryotic genes.

DOI: 10.1038/s41556-022-00847-6

Year: 2022

Chromatin micromanipulation in live cells

DOI: 10.1016/j.bpj.2021.11.1875

Year: 2022

Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging.

DOI: 10.1126/science.abn6583

Year: 2022

Transcription shapes 3D chromatin organization by interacting with loop-extruding cohesin complexes

DOI: 10.1101/2022.01.07.475367

Year: 2022

Promoter and enhancer RNAs regulate chromatin reorganization and activation of miR-10b/HOXD locus, and neoplastic transformation in glioma.

DOI: 10.1016/j.molcel.2022.03.018

Year: 2022

Fractal polymer with loops recapitulates key features of chromosome organization

DOI: 10.1101/2022.02.01.478588

Year: 2022

DNA-loop extruding SMC complexes can traverse one another in vivo

DOI: 10.21203/rs.3.rs-99064/v1

Year: 2021

Mechanisms of Chromosome Folding and Nuclear Organization: Their Interplay and Open Questions.

DOI: 10.1101/cshperspect.a040147

Year: 2021

Cells use loop extrusion to weave and tie the genome.

DOI: 10.1038/d41586-021-00351-1

Year: 2021

Keeping chromatin in the loop(s).

DOI: 10.1038/s41580-021-00337-x

Year: 2021

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