J. silvio Gutkind - Nanotechnology

Author Information

J. Silvio Gutkind is a distinguished researcher affiliated with the Department of Pharmacology at UCSD Moores Cancer Center, La Jolla, California. His research primarily focuses on the intricate mechanisms of G protein-coupled receptors (GPCRs) and their implications in cancer immunotherapy and cell signaling.

Research Contributions

J. Silvio Gutkind has made significant contributions to the field of nanotechnology and cellular signaling. His research has elucidated the role of G protein-regulated endocytic trafficking of adenylyl cyclase type 9 and the signaling pathways involving PDZ-RhoGEF and Cdc42. Notably, his work on the Onco-GPCRome has opened new avenues for targeting GPCR-driven oncocrine networks in cancer immunotherapy. His studies have also provided deep insights into the selectivity of G-protein coupling in GPCRs and the structural analysis of signaling scaffolds using cryo-electron microscopy.

Aliases

J. Silvio Gutkind is also known by several aliases including J Silvio Gutkind, Jsilvio Gutkind, J. Silvio Gutkind, J. S. Gutkind, J. Gutkind, J.silvio Gutkind, Js Gutkind, and J S Gutkind.

Publication and Citation Metrics

Metric Value
Citation Count 38,165
H-index 96
Paper Count 334

Publications:

DOI: 10.1074/jbc.AC120.015204

Year: 2020

DOI: 10.1074/jbc.AC120.015204

Year: 2020

DOI: 10.1016/j.cell.2019.04.044

Year: 2019

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