Federica Sotgia - Nanotechnology

Author Information

Federica Sotgia is a distinguished researcher affiliated with the Translational Medicine, School of Science, Engineering and Environment (SEE), University of Salford, Greater Manchester, UK. She has made significant contributions to the field of nanotechnology and cancer research, focusing on mechanisms of cancer metastasis and drug resistance.

Research Contributions

Federica Sotgia has extensively studied various aspects of cancer biology, particularly breast cancer. Her research has provided new insights into the role of stromal caveolin 1 in breast cancer spread to axillary lymph nodes and the implications of high ATP production in cancer drug resistance and metastasis. She has also investigated the potential of mitochondrial ATP depletion therapy, the anti-tumor and anti-metastatic activity of metabolic inhibitors, and the role of cholesterol and mevalonate in breast cancer progression. Additionally, her work has explored the targeting of cancer stem cells (CSCs) and the impact of mitochondrial fission on breast cancer stem cell activity. Notably, she has also considered the potential of senolytics and other anti-aging drugs in the context of COVID-19 treatment and prevention.

Aliases

Federica Sotgia is also known by the aliases F Sotgia and F. Sotgia.

Publication and Citation Metrics

Metric	Value
Total Citation Count	23,666
H-Index	85
Total Paper Count	244

Publications:

New insights in the expression of stromal caveolin 1 in breast cancer spread to axillary lymph nodes

DOI: 10.1038/s41598-021-82405-y

Year: 2021

High ATP Production Fuels Cancer Drug Resistance and Metastasis: Implications for Mitochondrial ATP Depletion Therapy

DOI: 10.3389/fonc.2021.740720

Year: 2021

MitoTracker Deep Red (MTDR) Is a Metabolic Inhibitor for Targeting Mitochondria and Eradicating Cancer Stem Cells (CSCs), With Anti-Tumor and Anti-Metastatic Activity In Vivo

DOI: 10.3389/fonc.2021.678343

Year: 2021

Bedaquiline, an FDA-approved drug, inhibits mitochondrial ATP production and metastasis in vivo, by targeting the gamma subunit (ATP5F1C) of the ATP synthase

DOI: 10.1038/s41418-021-00788-x

Year: 2021

A Myristoyl Amide Derivative of Doxycycline Potently Targets Cancer Stem Cells (CSCs) and Prevents Spontaneous Metastasis, Without Retaining Antibiotic Activity

DOI: 10.3389/fonc.2020.01528

Year: 2020

First-in-class candidate therapeutics that target mitochondria and effectively prevent cancer cell metastasis: mitoriboscins and TPP compounds

DOI: 10.18632/aging.103336

Year: 2020

COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection?

DOI: 10.18632/aging.103001

Year: 2020

Cholesterol and Mevalonate: Two Metabolites Involved in Breast Cancer Progression and Drug Resistance through the ERRα Pathway

DOI: 10.3390/cells9081819

Year: 2020

Mitochondrial Fission Factor (MFF) Inhibits Mitochondrial Metabolism and Reduces Breast Cancer Stem Cell (CSC) Activity

DOI: 10.3389/fonc.2020.01776

Year: 2020

Essential role of STAT5a in DCIS formation and invasion following estrogen treatment

DOI: 10.18632/aging.103586

Year: 2020

What are the Applications of Nanotechnology-Enhanced Radar?

How is ML Used in Nanomaterials Discovery?

What is Spectroscopic Ellipsometry?

How Does Micro Milling Work?

Why is PEI Effective for Gene Delivery?

What Role Do Wave-Like Properties Play in Nanosensors?

Why Use Logic Programming for Nanoscale Simulations?

What are Self-Assembling Nanostructures?

How is NEGF Applied in Practice?

How Does GAS Work?

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