carl wu - Nanotechnology

Author Information

Carl Wu is a prominent researcher affiliated with the Department of Biology at Johns Hopkins University and the Department of Molecular Biology and Genetics at the Johns Hopkins School of Medicine in Baltimore, MD. His research primarily focuses on chromatin dynamics, transcription regulation, and the mechanisms of chromatin remodelers.

Research Contributions

Carl Wu has made significant contributions to our understanding of chromatin dynamics and the molecular mechanisms underlying transcription regulation. His recent work has provided insights into the role of ATP binding in facilitating target search by chromatin remodelers, the recruitment and spread of the FACT complex in a Chd1-dependent manner, and the coordination of transcription preinitiation complex assembly in live cells. His research employs advanced techniques such as single-molecule imaging to elucidate the fast kinetics of chromatin remodelers and the dynamics of DNA and histones during chromatin remodeling processes.

Aliases

There are no aliases provided for Carl Wu.

Publication and Citation Metrics

Metric	Value
Citation Count	19,238
H-index	59
Paper Count	113

Publications:

ATP Binding Facilitates Target Search of SWR1 Chromatin Remodeler by Promoting One-Dimensional Diffusion on DNA

DOI: 10.1101/2022.01.24.477290

Year: 2022

FACT is recruited to the +1 nucleosome of transcribed genes and spreads in a Chd1-dependent manner.

DOI: 10.1016/j.molcel.2021.07.010

Year: 2021

Spatiotemporal coordination of transcription preinitiation complex assembly in live cells.

DOI: 10.1016/j.molcel.2021.07.022

Year: 2021

DNA Dynamics During SWR1-Catalyzed H2A.Z Histone Exchange

DOI: 10.1016/J.BPJ.2020.11.1040

Year: 2021

SMT Datasets from: Jeronimo et al., 2021. "FACT is recruited to the +1 nucleosome of transcribed genes and spreads in a Chd1-dependent manner"

DOI: 10.17632/RNF4NC3G6Y.1

Year: 2021

Single-molecule imaging of chromatin remodelers reveals role of ATPase in promoting fast kinetics of target search and dissociation from chromatin

DOI: 10.7554/eLife.69387

Year: 2021

Author response: Single-molecule imaging of chromatin remodelers reveals role of ATPase in promoting fast kinetics of target search and dissociation from chromatin

DOI: 10.7554/elife.69387.sa2

Year: 2021

Single-molecule imaging of chromatin remodelers reveals role of ATPase in promoting fast kinetics of target search and dissociation from chromatin

DOI: 10.1101/2021.04.21.440742

Year: 2021

Kinetic principles underlying pioneer function of GAGA transcription factor in live cells

DOI: 10.1101/2021.10.21.465351

Year: 2021

Coordinated DNA and Histone Dynamics Drive Accurate Histone H2A.Z Exchange

DOI: 10.1101/2021.10.22.465479

Year: 2021

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