Christoph M Fahlke - Nanotechnology

Author Information

Christoph Fahlke is affiliated with the Institute of Biological Information Processing, Molekular- und Zellphysiologie (IBI-1) at Forschungszentrum Jülich in Jülich, Germany. His research primarily focuses on the molecular mechanisms of ion transport and homeostasis, with a particular interest in the physiology and pathophysiology of ion channels and transporters in the nervous system.

Research Contributions

Christoph Fahlke has made significant contributions to the understanding of ion channel and transporter functions, particularly in the nervous system. His recent work includes studying the mechanisms of CLC anion/proton exchangers in secretory vesicle filling and granule exocytosis, the regulation of glial chloride homeostasis under ischemic stress, and the molecular basis of coupled transport and anion conduction in excitatory amino acid transporters. Additionally, he has explored the effects of mutations associated with epileptic encephalopathy on EAAT2 anion channel function and the impact of astrocyte ion homeostasis on stroke-induced brain damage.

Aliases

Christoph Fahlke is also known by several aliases including C Fahlke, Christoph M Fahlke, Ch. Fahlke, and C. Fahlke.

Publication and Citation Metrics

Metric	Value
Citation Count	6454
h-index	48
Paper Count	181

Publications:

CLC Anion/Proton Exchangers Regulate Secretory Vesicle Filling and Granule Exocytosis in Chromaffin Cells

DOI: 10.1523/JNEUROSCI.2439-21.2022

Year: 2022

Mechanisms Underlying Proton Release in CLC-type F-/H+ Antiporters.

DOI: 10.1021/acs.jpclett.1c00361

Year: 2021

Glial Chloride Homeostasis Under Transient Ischemic Stress

DOI: 10.3389/fncel.2021.735300

Year: 2021

Cellular Physiology and Pathophysiology of EAAT Anion Channels

DOI: 10.3389/fncel.2021.815279

Year: 2021

The molecular and phenotypic spectrum of CLCN4‐related epilepsy

DOI: 10.1111/epi.16906

Year: 2021

Excitatory Amino Acid Transporter EAAT5 Improves Temporal Resolution in the Retina

DOI: 10.1523/ENEURO.0406-21.2021

Year: 2021

Determination of protein stoichiometries via dual-color colocalization with single molecule localization microscopy

DOI: 10.1101/2021.10.05.463155

Year: 2021

Molecular Basis of Coupled Transport and Anion Conduction in Excitatory Amino Acid Transporters

DOI: 10.1007/s11064-021-03252-x

Year: 2021

Mutations associated with epileptic encephalopathy modify EAAT2 anion channel function

DOI: 10.1111/epi.17154

Year: 2021

Dysregulation of Astrocyte Ion Homeostasis and Its Relevance for Stroke-Induced Brain Damage

DOI: 10.3390/ijms22115679

Year: 2021

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