Precision medicine - Nanotechnology

What is Precision Medicine?

Precision medicine is a revolutionary approach that tailors medical treatment to the individual characteristics of each patient. This can include genetic, environmental, and lifestyle factors. By focusing on the unique aspects of each patient, precision medicine seeks to optimize therapeutic efficacy and minimize adverse effects.

How Does Nanotechnology Contribute to Precision Medicine?

Nanotechnology, involving the manipulation of materials on an atomic or molecular scale, offers numerous advantages for precision medicine. It enables the development of nanoscale drug delivery systems, diagnostic tools, and therapeutic agents that can interact with biological systems at a molecular level.

What are Nanoscale Drug Delivery Systems?

Nanoscale drug delivery systems are designed to deliver drugs with high specificity and efficiency. These systems can target specific cells or tissues, reduce drug toxicity, and improve the bioavailability of therapeutics. Examples include liposomes, dendrimers, and polymeric nanoparticles.

How Do Nanoparticles Enhance Diagnostic Tools?

Nanoparticles can be used to develop highly sensitive and specific diagnostic tools. For instance, quantum dots and gold nanoparticles can be employed in imaging techniques to detect diseases at an early stage. These nanoparticles can bind to specific markers associated with diseases, providing precise and rapid diagnosis.

What Role Do Nanomaterials Play in Therapeutic Agents?

Nanomaterials can be engineered to function as therapeutic agents. For example, nanocarriers can transport drugs directly to cancer cells, minimizing damage to healthy tissues. Additionally, nanoparticles can be used to deliver genetic material for gene therapy, offering potential cures for genetic disorders.

What are the Challenges in Using Nanotechnology for Precision Medicine?

Despite its potential, the integration of nanotechnology in precision medicine faces several challenges. These include biocompatibility, potential toxicity, and regulatory hurdles. Ensuring that nanoparticles do not elicit adverse immune responses and can be safely eliminated from the body are critical areas of ongoing research.

What is the Future of Nanotechnology in Precision Medicine?

The future of nanotechnology in precision medicine is promising. Advances in nanofabrication techniques and nanoinformatics are expected to lead to more sophisticated and effective medical applications. Personalized nanomedicine, where treatments are specifically designed based on an individual's genetic profile, holds great potential for revolutionizing healthcare.

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Frequency of pharmacogenomic variation and medication exposures among All of Us Participants.

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Molecular Basis and Diagnostic Approach to Isolated and Syndromic Lateralized Overgrowth in Childhood.

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Digital twins: reimagining the future of cardiovascular risk prediction and personalised care.

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Activation of the hypoxia response in the aging cerebrovasculature protects males against cognitive impairment.

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Personalized evaluation of the passive myocardium in ischemic cardiomyopathy via computational modeling using Bayesian optimization.

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In vivo detection of Alzheimer\'s and Lewy body disease concurrence: Clinical implications and future perspectives.

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A large study of metabolomics reveals common and distinct metabolic biomarkers for type 2 diabetes, coronary heart disease, and stroke.

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Candidate prognostic biomarkers and prediction models for high-grade serous ovarian cancer from urinary proteomics.

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Recent advances on thermosensitive hydrogels-mediated precision therapy.

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Impact of high-salt diet in health and diseases and its role in pursuit of cancer immunotherapy by modulating gut microbiome.

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Efficient isolation of encoded microparticles in a degassed micromold for highly sensitive and multiplex immunoassay with signal amplification.

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Exploring gender differences in pharmacokinetics of central nervous system related medicines based on a systematic review approach.

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Random forest differentiation of Escherichia coli in elderly sepsis using biomarkers and infectious sites.

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Integrating system biology and intratumor gene therapy by trans-complementing the appropriate co-stimulatory molecule as payload in oncolytic herpes virus.

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Precision-guided treatment in high-risk pediatric cancers.

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Current Management of Allergic Rhinitis.

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SpliceAPP: an interactive web server to predict splicing errors arising from human mutations.

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Advances in nanobubbles for cancer theranostics: Delivery, imaging and therapy.

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Application of comprehensive molecular genetic profiling in precision cancer medicine, Hungarian experiences.

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Advancements in nanomedicine: Precision delivery strategies for male pelvic malignancies - Spotlight on prostate and colorectal cancer.

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